https://www.innosci.org/IJNRAS <div> <p style="text-align: justify;"><strong>Vital Annex: International Journal of Novel Research in Advanced Sciences (2751-756X)</strong> is open access peer-reviewed monthly journal. This journal covers the multidimensional scope of research while investigating major points of contemporary issues. The journal targets promoting advanced research in various disciplines of all scientific areas Research journal invites authors to submit novelty papers from multidisciplinary disciplines of both applied and theoretical research.</p> </div> en-US editor@innosci.org (Joao Abreu) editor@innosci.org (Editor in Chief) Mon, 13 May 2024 05:41:10 -0600 OJS 3.3.0.8 http://blogs.law.harvard.edu/tech/rss 60 https://www.innosci.org/IJNRAS/article/view/2003 <p>The dissemination of multidrug-resistant uropathogenic Escherichia coli (UPEC) poses a significant challenge in healthcare settings. This study aimed to investigate the potential of palmitic acid, extracted from sunflower seeds, as an inhibitor against UPEC. Ethyl acetate, yielding the highest palmitic acid content, was utilized for extraction, followed by purification using silica gel. Characterization through thin-layer chromatography, UV-Visspectrometer, and FTIR confirmed the identity of palmitic acid. UPEC isolates from UTI patients were identified using the VITEK 2 system. Evaluation of palmitic acid and ciprofloxacin efficacy against UPEC revealed palmitic acid as the most effective inhibitor, with MICs ranging from 8 to 64 μg/ml, compared to ciprofloxacin's 64 to 512 μg/ml. Palmitic acid's bactericidal activity highlights its potential as an alternative therapeutic agent against multidrug-resistant UPEC strains, addressing a critical knowledge gap in combating UPEC infections. This research underscores the importance of exploring natural compounds like palmitic acid for their therapeutic potential, offering promising implications for the development of novel antimicrobial strategies against UPEC infections.</p> Hala M. Sabre Copyright (c) 2024 Vital Annex: International Journal of Novel Research in Advanced Sciences https://www.innosci.org/IJNRAS/article/view/2003 Mon, 13 May 2024 00:00:00 -0600